Endocrine Abstracts

In our study we included retrospective analyses of 101 patients (mean age 35 years, 85 women and 16 men) with Cushing’s disease (CD), who underwent transsphenoidal surgery (TSS) treatment. CD is based on clinical suspicion, hormonal research of cortisol (F), ACTH, 24-hous urine F, results of dexamethasone suppression tests low (1 mg) dose (LDDST) and high (8 mg) dose (HDDST) and MR-imaging (MRI). Before the operation all patients have high F, ACTH, negative LDDST and posi...